EC |
2.1.1.9 |
Accepted name: |
thiol S-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a methyl thioether |
Other name(s): |
S-methyltransferase; thiol methyltransferase; TMT |
Systematic name: |
S-adenosyl-L-methionine:thiol S-methyltransferase |
Comments: |
H2S and a variety of alkyl, aryl and heterocyclic thiols and hydroxy thiols can act as acceptors. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9029-81-6 |
References: |
1. |
Borchardt, R.T. and Cheng, C.F. Purification and characterization of rat liver microsomal thiol methyltransferase. Biochim. Biophys. Acta 522 (1978) 340–353. [DOI] [PMID: 623768] |
2. |
Bremer, J. and Greenberg, D.M. Enzymic methylation of foreign sulfhydryl compounds. Biochim. Biophys. Acta 46 (1961) 217–224. |
3. |
Weisiger, R.A. and Jakoby, W.B. Thiol S-methyltransferase from rat liver. Arch. Biochem. Biophys. 196 (1979) 631–637. [DOI] [PMID: 485170] |
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[EC 2.1.1.9 created 1965] |
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