EC |
2.1.1.393 |
Accepted name: |
ajmaline N-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + ajmaline = S-adenosyl-L-homocysteine + 4-methylajmaline |
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For diagram of ajmaline, vinorine, vomilenine and raucaffricine biosynthesis, click here |
Glossary: |
4-methylajmaline = Nβ-methylajmaline |
Other name(s): |
RsANMT |
Systematic name: |
S-adenosyl-L-methionine:ajmaline N-methyltransferase |
Comments: |
Isolated from the plant Rauvolfia serpentina (Indian snakeroot). The enzyme can also methylate norajmaline, with lower activity. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Cazares-Flores, P., Levac, D. and De Luca, V. Rauvolfia serpentina N-methyltransferases involved in ajmaline and Nβ-methylajmaline biosynthesis belong to a gene family derived from γ-tocopherol C-methyltransferase. Plant J. 87 (2016) 335–342. [DOI] [PMID: 27122470] |
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[EC 2.1.1.393 created 2024] |
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