The Enzyme Database

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EC 2.1.1.393     
Accepted name: ajmaline N-methyltransferase
Reaction: S-adenosyl-L-methionine + ajmaline = S-adenosyl-L-homocysteine + 4-methylajmaline
For diagram of ajmaline, vinorine, vomilenine and raucaffricine biosynthesis, click here
Glossary: 4-methylajmaline = Nβ-methylajmaline
Other name(s): RsANMT
Systematic name: S-adenosyl-L-methionine:ajmaline N-methyltransferase
Comments: Isolated from the plant Rauvolfia serpentina (Indian snakeroot). The enzyme can also methylate norajmaline, with lower activity.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Cazares-Flores, P., Levac, D. and De Luca, V. Rauvolfia serpentina N-methyltransferases involved in ajmaline and Nβ-methylajmaline biosynthesis belong to a gene family derived from γ-tocopherol C-methyltransferase. Plant J. 87 (2016) 335–342. [DOI] [PMID: 27122470]
[EC 2.1.1.393 created 2024]
 
 


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