EC |
2.1.1.392 |
Accepted name: |
norajmaline N-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + norajmaline = S-adenosyl-L-homocysteine + ajmaline |
|
For diagram of ajmaline, vinorine, vomilenine and raucaffricine biosynthesis, click here |
Other name(s): |
NNMT (gene name) |
Systematic name: |
S-adenosyl-L-methionine:norajmaline N-methyltransferase |
Comments: |
The enzyme, characterized from the plant Rauvolfia serpentina (Indian snakeroot), catalyses the last step in the pathway for the biosynthesis of the monoterpenoid indole alkaloid ajmaline. Also reacts with 4-methylnorajmaline. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Cazares-Flores, P., Levac, D. and De Luca, V. Rauvolfia serpentina N-methyltransferases involved in ajmaline and Nβ-methylajmaline biosynthesis belong to a gene family derived from γ-tocopherol C-methyltransferase. Plant J. 87 (2016) 335–342. [DOI] [PMID: 27122470] |
|
[EC 2.1.1.392 created 2024] |
|
|
|
|