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Your query returned 1 entry. 
Printable version
| EC | 2.1.1.340 | ||||
| Accepted name: | 3-aminomethylindole N-methyltransferase | ||||
| Reaction: | 2 S-adenosyl-L-methionine + 3-(aminomethyl)indole = 2 S-adenosyl-L-homocysteine + gramine (overall reaction) (1a) S-adenosyl-L-methionine + 3-(aminomethyl)indole = S-adenosyl-L-homocysteine + (1H-indol-3-yl)-N-methylmethanamine (1b) S-adenosyl-L-methionine + (1H-indol-3-yl)-N-methylmethanamine = S-adenosyl-L-homocysteine + gramine |
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| For diagram of gramine biosynthesis, click here | |||||
| Glossary: | 3-(aminomethyl)indole = (1H-indol-3-yl)methanamine gramine = (1H-indol-3-ylmethyl)dimethylamine = (1H-indol-3-yl)-N,N-dimethylmethanamine |
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| Other name(s): | NMT (gene name) | ||||
| Systematic name: | S-adenosyl-L-methionine:3-(aminomethyl)indole N-methyltransferase (gramine-forming) | ||||
| Comments: | The enzyme, characterized from Hordeum vulgare (barley), catalyses two successive N-methylation reactions during the biosynthesis of gramine, a toxic indole alkaloid. | ||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
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