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Your query returned 1 entry. Printable version
EC | 2.1.1.337 | ||
Accepted name: | reticuline N-methyltransferase | ||
Reaction: | (1) S-adenosyl-L-methionine + (S)-reticuline = S-adenosyl-L-homocysteine + (S)-tembetarine (2) S-adenosyl-L-methionine + (S)-corytuberine = S-adenosyl-L-homocysteine + (S)-magnoflorine |
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For diagram of corytuberine and magnoflorine biosynthesis, click here and for diagram of tembetarine biosynthesis, click here | |||
Glossary: | (S)-reticuline = (1S)-1-(3-hydroxy-4-methoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol (S)-tembetarine = (1S)-1-(3-hydroxy-4-methoxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-ol (S)-corytuberine = (6aS)-2,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,11-diol (S)-magnoflorine = (6aS)-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium |
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Other name(s): | RNMT | ||
Systematic name: | S-adenosyl-L-methionine:(S)-reticuline N-methyltransferase | ||
Comments: | The enzyme from opium poppy (Papaver somniferum) can also methylate (R)-reticuline, tetrahydropapaverine, (S)-glaucine and (S)-bulbocapnine. It is involved in the biosynthesis of the quaternary benzylisoquinoline alkaloid magnoflorine. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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