The Enzyme Database

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Accepted name: tRNA (guanine6-N2)-methyltransferase
Reaction: S-adenosyl-L-methionine + guanine6 in tRNA = S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA
Other name(s): methyltransferase Trm14; m2G6 methyltransferase
Systematic name: S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase
Comments: The enzyme specifically methylates guanine6 at N2 in tRNA.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB
1.  Menezes, S., Gaston, K.W., Krivos, K.L., Apolinario, E.E., Reich, N.O., Sowers, K.R., Limbach, P.A. and Perona, J.J. Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. Nucleic Acids Res. 39 (2011) 7641–7655. [DOI] [PMID: 21693558]
[EC created 2012]

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