ExplorEnz: EC 2.1.1.240

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2.1.1.240

Accepted name:

trans-resveratrol di-O-methyltransferase

Reaction:

2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction)
(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4′,5-dihydroxy-trans-stilbene
(1b) S-adenosyl-L-methionine + 3-methoxy-4′,5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene

For diagram of chalcone and stilbene biosynthesis, click here

Glossary:

3-methoxy-4′,5-dihydroxy-trans-stilbene = resveratrol monomethyl ether
pterostilbene = 3,5-dimethoxy-4′-hydroxy-trans-stilbene
trans-resveratrol = 3,4′,5-trihydroxy-trans-stilbene

Other name(s):

ROMT; resveratrol O-methyltransferase; pterostilbene synthase

Systematic name:

S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase

Comments:

The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.

Links to other databases:

BRENDA, EXPASY, Gene, KEGG, MetaCyc

References:

Schmidlin, L., Poutaraud, A., Claudel, P., Mestre, P., Prado, E., Santos-Rosa, M., Wiedemann-Merdinoglu, S., Karst, F., Merdinoglu, D. and Hugueney, P. A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine. Plant Physiol. 148 (2008) 1630–1639. [DOI] [PMID: 18799660]

[EC 2.1.1.240 created 2012]