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Your query returned 1 entry. Printable version
EC | 2.1.1.164 | ||||
Accepted name: | demethylrebeccamycin-D-glucose O-methyltransferase | ||||
Reaction: | 4′-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine | ||||
For diagram of rebeccamycin biosynthesis, click here | |||||
Other name(s): | RebM | ||||
Systematic name: | S-adenosyl-L-methionine:demethylrebeccamycin-D-glucose O-methyltransferase | ||||
Comments: | Catalyses the last step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is able to use a wide variety substrates, tolerating variation on the imide heterocycle, deoxygenation of the sugar moiety, and even indolocarbazole glycoside anomers [1]. The enzyme is a member of the general acid/base-dependent O-methyltransferase family [2]. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||
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