EC |
2.1.1.16 |
Accepted name: |
methylene-fatty-acyl-phospholipid synthase |
Reaction: |
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid |
Other name(s): |
unsaturated-phospholipid methyltransferase |
Systematic name: |
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating) |
Comments: |
The enzyme transfers a methyl group to the 10-position of a Δ-olefinic acyl chain in phosphatidylglycerol or phosphatidylinositol or, more slowly, phosphatidylethanolamine; subsequent proton transfer produces a 10-methylene group (cf. EC 2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase). |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 37256-90-9 |
References: |
1. |
Akamatsu, Y. and Law, J.H. Enzymatic alkylenation of phospholipid fatty acid chains by extracts of Mycobacterium phlei. J. Biol. Chem. 245 (1970) 701–708. [PMID: 4313604] |
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[EC 2.1.1.16 created 1972, modified 1986] |
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