Accepted name: selenate reductase
Reaction: selenite + H2O + acceptor = selenate + reduced acceptor
Systematic name: selenite:reduced acceptor oxidoreductase
Comments: The periplasmic enzyme from Thauera selenatis is a complex comprising three heterologous subunits (α, β and γ) that contains molybdenum, iron, acid-labile sulfide and heme b as cofactor constituents. Nitrate, nitrite, chlorate and sulfate are not substrates. A number of compounds, including acetate, lactate, pyruvate, and certain sugars, amino acids, fatty acids, di- and tricarboxylic acids, and benzoate can serve as electron donors.
1.  Schröder, I., Rech, S., Krafft, T. and Macy, J.M. Purification and characterization of the selenate reductase from Thauera selenatis. J. Biol. Chem. 272 (1997) 23765–23768. [PMID: 9295321]
2.  Macy, J.M., Rech, S., Auling, G., Dorsch, M., Stackebrandt, E. and Sly, L.I. Thauera selenatis gen. nov., sp. nov., a member of the β subclass of Proteobacteria with a novel type of anaerobic respiration. Int. J. Syst. Bacteriol. 43 (1993) 135–142. [PMID: 8427805]
3.  Krafft, T., Bowen, A., Theis, F. and Macy, J.M. Cloning and sequencing of the genes encoding the periplasmic-cytochrome B-containing selenate reductase of Thauera selenatis. DNA 10 (2000) 365–377. [PMID: 10826693]
4.  Stolz, J.F. and Oremland, R.S. Bacterial respiration of arsenic and selenium. FEMS Microbiol. Rev. 23 (1999) 615–627. [PMID: 10525169]
[EC created 2003]