The Enzyme Database

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Accepted name: GMP reductase
Reaction: IMP + NH3 + NADP+ = GMP + NADPH + H+
Glossary: IMP = inosine 5′-phosphate
GMP = guanosine 5′-phosphate
Other name(s): guanosine 5′-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5′-phosphate oxidoreductase (deaminating); guanosine 5′-phosphate reductase
Systematic name: inosine-5′-phosphate:NADP+ oxidoreductase (aminating)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9029-32-7
1.  MacKenzie, J.J. and Sorensen, L.B. Guanosine 5′-phosphate reductase of human erythrocytes. Biochim. Biophys. Acta 327 (1973) 282–294. [DOI] [PMID: 4149840]
2.  Mager, J. and Magasanik, B. Guanosine 5′-phosphate reductase and its role in the interconversion of purine nucleotides. J. Biol. Chem. 235 (1960) 1474–1478. [PMID: 14419794]
[EC created 1965 as EC, transferred 2002 to EC]

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