The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: NADH oxidase (H2O-forming)
Reaction: 2 NADH + 2 H+ + O2 = 2 NAD+ + 2 H2O
Other name(s): H2O-forming NADH oxidase; Nox-2
Systematic name: NADH:oxygen oxidoreductase (H2O-forming)
Comments: A flavoprotein (FAD). The bacterium Streptococcus mutans contains two distinct NADH oxidases, a H2O-forming enzyme and a H2O2-forming enzyme (cf. EC, NADH oxidase (H2O2-forming)) [1].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Schmidt, H.L., Stocklein, W., Danzer, J., Kirch, P. and Limbach, B. Isolation and properties of an H2O-forming NADH oxidase from Streptococcus faecalis. Eur. J. Biochem. 156 (1986) 149–155. [DOI] [PMID: 3082630]
2.  Higuchi, M., Shimada, M., Yamamoto, Y., Hayashi, T., Koga, T. and Kamio, Y. Identification of two distinct NADH oxidases corresponding to H2O2-forming oxidase and H2O-forming oxidase induced in Streptococcus mutans. J. Gen. Microbiol. 139 (1993) 2343–2351. [DOI] [PMID: 8254304]
3.  Matsumoto, J., Higuchi, M., Shimada, M., Yamamoto, Y. and Kamio, Y. Molecular cloning and sequence analysis of the gene encoding the H2O-forming NADH oxidase from Streptococcus mutans. Biosci. Biotechnol. Biochem. 60 (1996) 39–43. [DOI] [PMID: 8824824]
4.  Kawasaki, S., Ishikura, J., Chiba, D., Nishino, T. and Niimura, Y. Purification and characterization of an H2O-forming NADH oxidase from Clostridium aminovalericum: existence of an oxygen-detoxifying enzyme in an obligate anaerobic bacteria. Arch. Microbiol. 181 (2004) 324–330. [DOI] [PMID: 15014929]
5.  Zhang, Y.W., Tiwari, M.K., Gao, H., Dhiman, S.S., Jeya, M. and Lee, J.K. Cloning and characterization of a thermostable H2O-forming NADH oxidase from Lactobacillus rhamnosus. Enzyme Microb. Technol. 50 (2012) 255–262. [DOI] [PMID: 22418266]
[EC created 2013]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald