ExplorEnz: EC 1.5.3.18

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1.5.3.18

Accepted name:

L-saccharopine oxidase

Reaction:

N⁶-(L-1,3-dicarboxypropyl)-L-lysine + H₂O + O₂ = (S)-2-amino-6-oxohexanoate + L-glutamate + H₂O₂

Glossary:

L-saccharopine = N⁶-(L-1,3-dicarboxypropyl)-L-lysine
(S)-2-amino-6-oxohexanoate = L-2-aminoadipate 6-semialdehyde = L-allysine

Other name(s):

FAP2

Systematic name:

L-saccharopine:oxygen oxidoreductase (L-glutamate-forming)

Comments:

The enzyme is involved in pipecolic acid biosynthesis. A flavoprotein (FAD).

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Yoshida, N., Akazawa, S., Katsuragi, T. and Tani, Y. Characterization of two fructosyl-amino acid oxidase homologs of Schizosaccharomyces pombe. J. Biosci. Bioeng. 97 (2004) 278–280. [DOI] [PMID: 16233628]
2.	Wickwire, B.M., Wagner, C. and Broquist, H.P. Pipecolic acid biosynthesis in Rhizoctonia leguminicola. II. Saccharopine oxidase: a unique flavin enzyme involved in pipecolic acid biosynthesis. J. Biol. Chem. 265 (1990) 14748–14753. [PMID: 2394693]

[EC 1.5.3.18 created 2011]