The Enzyme Database

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Accepted name: FMN reductase [NAD(P)H]
Reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+
For diagram of FAD biosynthesis, click here
Other name(s): FRG
Systematic name: FMNH2:NAD(P)+ oxidoreductase
Comments: Contains FMN. The enzyme can utilize NADH and NADPH with similar reaction rates. Different from EC, FMN reductase (NADH) and EC, FMN reductase (NADPH). The luminescent bacterium Vibrio harveyi possesses all three enzymes [1]. Also reduces riboflavin and FAD, but more slowly.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB
1.  Watanabe, H. and Hastings, J.W. Specificities and properties of three reduced pyridine nucleotide-flavin mononucleotide reductases coupling to bacterial luciferase. Mol. Cell. Biochem. 44 (1982) 181–187. [PMID: 6981058]
[EC created 2011]

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