Accepted name: thiomorpholine-carboxylate dehydrogenase
Reaction: thiomorpholine 3-carboxylate + NAD(P)+ = 3,4-dehydro-thiomorpholine-3-carboxylate + NAD(P)H + H+
Other name(s): ketimine reductase; ketimine-reducing enzyme
Systematic name: thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase
Comments: The product is the cyclic imine of the 2-oxoacid corresponding to S-(2-aminoethyl)cysteine. In the reverse direction, a number of other cyclic unsaturated compounds can act as substrates, but more slowly.
1.  Nardini, M., Ricci, G., Caccuri, A.M., Solinas, S.P., Vesci, L. and Cavallini, D. Purification and characterization of a ketimine-reducing enzyme. Eur. J. Biochem. 173 (1988) 689–694. [PMID: 3371353]
[EC created 1990]

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