| EC |
1.5.1.18 |
| Accepted name: |
ephedrine dehydrogenase |
| Reaction: |
(-)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + NADH + H+ |
| Systematic name: |
(-)-ephedrine:NAD+ 2-oxidoreductase |
| Comments: |
The product immediately hydrolyses to methylamine and 1-hydroxy-1-phenylpropan-2-one. Acts on a number of related compounds including (-)-sympatol, (+)-pseudoephedrine and (+)-norephedrine. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 73508-06-2 |
| References: |
| 1. |
Klamann, E. and Lingens, F. Degradation of (-)-ephedrine by Pseudomonas putida. Detection of (-)-ephedrine: NAD+-oxidoreductase from Arthrobacter globiformis. Z. Naturforsch. C: Biosci. 35 (1980) 80–87. [PMID: 7405363] |
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| [EC 1.5.1.18 created 1984] |
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