The Enzyme Database

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Accepted name: D-lysopine dehydrogenase
Reaction: N2-(D-1-carboxyethyl)-L-lysine + NADP+ + H2O = L-lysine + pyruvate + NADPH + H+
Other name(s): D-lysopine synthase; lysopine dehydrogenase; D(+)-lysopine dehydrogenase; 2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
Systematic name: N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
Comments: In the reverse reaction, a number of L-amino acids can act instead of L-lysine, and 2-oxobutanoate and, to a lesser extent, glyoxylate can act instead of pyruvate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 65187-41-9
1.  Otten, L.A.B.M., Vreugdenhil, D. and Schilperoort, R.A. Properties of D(+)-lysopine dehydrogenase from crown gall tumour tissue. Biochim. Biophys. Acta 485 (1977) 268–277. [DOI] [PMID: 21695]
[EC created 1978]

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