EC |
1.4.1.9 |
Accepted name: |
leucine dehydrogenase |
Reaction: |
L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH + H+ |
Other name(s): |
L-leucine dehydrogenase; L-leucine:NAD+ oxidoreductase, deaminating; LeuDH |
Systematic name: |
L-leucine:NAD+ oxidoreductase (deaminating) |
Comments: |
Also acts on isoleucine, valine, norvaline and norleucine. |
Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9082-71-7 |
References: |
1. |
Sanwal, B.D. and Zink, M.W. L-Leucine dehydrogenase of Bacillus cereus. Arch. Biochem. Biophys. 94 (1961) 430–435. [DOI] [PMID: 13746411] |
2. |
Zink, M.W. and Sanwal, B.D. The distribution and substrate specificity of L-leucine dehydrogenase. Arch. Biochem. Biophys. 99 (1962) 72–77. |
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[EC 1.4.1.9 created 1972] |
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