|
Your query returned 1 entry. Printable version
EC | 1.3.1.115 | ||
Accepted name: | 3-oxocholoyl-CoA 4-desaturase | ||
Reaction: | (1) 7α,12α-dihydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7α,12α-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ (2) 7α-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7α-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ |
||
Glossary: | 7α,12α-dihydroxy-3-oxochol-24-oyl-CoA = 3-oxocholoyl-CoA 7α-hydroxy-3-oxochol-24-oyl-CoA = 3-oxochenodeoxycholoyl-CoA |
||
Other name(s): | baiCD (gene name); 3-oxo-choloyl-CoA dehydrogenase | ||
Systematic name: | 3-oxocholoyl-CoA Δ4-oxidoreductase | ||
Comments: | Contains flavin. The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7α-dehydroxylation pathway. The enzyme catalyses the stereo-specific oxidation of its substrates and has no activity with the 7β anomers. cf. EC 1.3.1.116, 7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
| ||