EC |
1.21.1.2 |
Accepted name: |
2,4-dichlorobenzoyl-CoA reductase |
Reaction: |
4-chlorobenzoyl-CoA + NADP+ + chloride = 2,4-dichlorobenzoyl-CoA + NADPH + H+ |
Systematic name: |
4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating) |
Comments: |
The enzyme, characterized from Corynebacterium strains able to grow on 2,4-dichlorobenzoate, forms part of the 2,4-dichlorobenzoate degradation pathway. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc |
References: |
1. |
Romanov, V. and Hausinger, R.P. NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strain NTB-1 via 2,4-dichlorobenzoyl coenzyme A. J. Bacteriol. 178 (1996) 2656–2661. [DOI] [PMID: 8626335] |
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[EC 1.21.1.2 created 2000 as EC 1.3.1.63, modified 2011, transferred 2015 to EC 1.21.1.2] |
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