| EC |
1.14.99.11 |
| Accepted name: |
estradiol 6β-monooxygenase |
| Reaction: |
estradiol-17β + reduced acceptor + O2 = 6β-hydroxyestradiol-17β + acceptor + H2O |
| Other name(s): |
estradiol 6β-hydroxylase |
| Systematic name: |
estradiol-17β,hydrogen-donor:oxygen oxidoreductase (6β-hydroxylating) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9029-70-3 |
| References: |
| 1. |
Haines, W.J. The biosynthesis of adrenal cortex hormones. Recent Progr. Hormone Res. 7 (1952) 255–305. |
| 2. |
Mueller, G.C. and Rumney, G. Formation of 6β-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes. J. Am. Chem. Soc. 79 (1957) 1004–1005. |
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| [EC 1.14.99.11 created 1965 as EC 1.14.1.10, transferred 1972 to EC 1.14.99.11] |
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