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Your query returned 1 entry. 
Printable version
| EC | 1.14.18.13 | ||||||
| Accepted name: | ortho-methoxyphenolase | ||||||
| Reaction: | (1) para-substituted 2-methoxyphenol + O2 = meta-substituted 3-methoxy-1,2-benzoquinone + H2O (2) 2 para-substituted 2,6-dimethoxyphenol + O2 = 2 meta-substituted 3-methoxy-1,2-benzoquinone + 2 methanol (3) 2 meta-substituted 3-methoxybenzene-1,2-diol + O2 = 2 meta-substituted 3-methoxy-1,2-benzoquinone + 2 H2O |
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| Systematic name: | an ortho-methoxylated phenol:oxygen oxidoreductase (ortho-quinone-forming) | ||||||
| Comments: | A group of coupled binuclear copper enzymes found in filamentous fungi. Unlike EC 1.14.18.1, tyrosinase, these enzymes exhibit a distinct preference for ortho-methoxylated phenolic compounds such as guaiacyl- and syringyl-type phenolics derived from lignin depolymerization. When acting on syringyl-type substrates (having two ortho-methoxy groups), but not on guaiacyl-type substrates (a single ortho-methoxy group), the enzyme catalyses oxidative demethoxylation releasing methanol. The enzymes accommodate a wide range of methoxylated phenolic substrates, with variability in the para-position substituent relative to the phenolic hydroxyl. | ||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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