| EC |
1.14.14.187 |
| Accepted name: |
rhazimal synthase |
| Reaction: |
geissoschizine + [reduced NADPH—hemoprotein reductase] + O2 = rhazimal + [oxidized NADPH—hemoprotein reductase] + 2 H2O |
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For diagram of akuammiline biosynthesis, click here |
| Other name(s): |
RHS (gene name) |
| Systematic name: |
geissoschizine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (rhazimal forming) |
| Comments: |
A heme-thiolate protein (P-450) isolated from the plant Alstonia scholaris (blackboard tree). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Wang, Z., Xiao, Y., Wu, S., Chen, J., Li, A. and Tatsis, E.C. Deciphering and reprogramming the cyclization regioselectivity in bifurcation of indole alkaloid biosynthesis. Chem. Sci. 13 (2022) 12389–12395. [DOI] [PMID: 36349266] |
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| [EC 1.14.14.187 created 2024] |
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