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Your query returned 1 entry. Printable version
EC | 1.14.14.138 | ||||||||
Accepted name: | lithocholate 6β-hydroxylase | ||||||||
Reaction: | lithocholate + [reduced NADPH—hemoprotein reductase] + O2 = 6β-hydroxylithocholate + [oxidized NADPH—hemoprotein reductase] + H2O | ||||||||
For diagram of the reaction of deoxycholate and related bile acids, click here | |||||||||
Glossary: | lithocholate = 3α-hydroxy-5β-cholan-24-oate 6β-hydroxylithocholate = murideoxycholate = 3α,6β-dihydroxy-5β-cholan-24-oate |
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Other name(s): | lithocholate 6β-monooxygenase; CYP3A10; 6β-hydroxylase; cytochrome P450 3A10; lithocholic acid 6β-hydroxylase | ||||||||
Systematic name: | lithocholate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (6β-hydroxylating) | ||||||||
Comments: | A cytochrome P-450 (heme-thiolate) protein from Mesocricetus auratus (golden hamster). Expression of the gene for this enzyme is 50-fold higher in male compared to female hamsters [1]. | ||||||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 9075-83-6 | ||||||||
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