EC |
1.14.14.102 |
Accepted name: |
N-methylcoclaurine 3′-monooxygenase |
Reaction: |
(S)-N-methylcoclaurine + [reduced NADPH—hemoprotein reductase] + O2 = (S)-3′-hydroxy-N-methylcoclaurine + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of reticuline biosynthesis, click here |
Other name(s): |
N-methylcoclaurine 3′-hydroxylase; CYP80B1 (gene name) |
Systematic name: |
(S)-N-methylcoclaurine,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (3′-hydroxylating) |
Comments: |
A cytochrome P-450 (heme-thiolate) protein involved in benzylisoquinoline alkaloid synthesis in higher plants. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 202420-37-9 |
References: |
1. |
Pauli, H.H. and Kutchan, T.M. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 13 (1998) 793–801. [DOI] [PMID: 9681018] |
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[EC 1.14.14.102 created 2001 as 1.14.13.71, transferred 2018 to EC 1.14.14.102] |
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