The Enzyme Database

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EC 1.14.13.245     
Accepted name: assimilatory dimethylsulfide S-monooxygenase
Reaction: (1) dimethyl sulfide + NADH + H+ + O2 = dimethyl sulfoxide + NAD+ + H2O
(2) dimethyl sulfoxide + NADH + H+ + O2 = dimethyl sulfone + NAD+ + H2O
Other name(s): dsoBCDEF (gene names)
Systematic name: dimethyl sulfide,NADH:oxygen oxidoreductase (S-oxidizing)
Comments: The enzyme, studied from the bacterium Acinetobacter sp. strain 20B, is very similar to EC 1.14.13.244, phenol 2-monooxygenase (NADH). It consists of a multisubunit oxygenease component that contains the active site and a dinuclear iron center, a reductase component that contains FAD and one iron-sulfur cluster, and a regulatory component. The three components comprise five different polypeptides. The enzyme catalyses the first two steps of a dimethyl sulfide oxidation pathway in this organism.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Horinouchi, M., Kasuga, K., Nojiri, H., Yamane, H. and Omori, T. Cloning and characterization of genes encoding an enzyme which oxidizes dimethyl sulfide in Acinetobacter sp. strain 20B. FEMS Microbiol. Lett. 155 (1997) 99–105. [PMID: 9345770]
2.  Horinouchi, M., Yoshida, T., Nojiri, H., Yamane, H. and Omori, T. Polypeptide requirement of multicomponent monooxygenase DsoABCDEF for dimethyl sulfide oxidizing activity. Biosci. Biotechnol. Biochem. 63 (1999) 1765–1771. [PMID: 26300166]
[EC 1.14.13.245 created 2019]
 
 


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