ExplorEnz: EC 1.14.13.219

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1.14.13.219

Accepted name:

resorcinol 4-hydroxylase (NADPH)

Reaction:

resorcinol + NADPH + H⁺ + O₂ = hydroxyquinol + NADP⁺ + H₂O

Glossary:

resorcinol = benzene-1,3-diol
hydroxyquinol = benzene-1,2,4-triol

Systematic name:

resorcinol,NADPH:oxygen oxidoreductase (4-hydroxylating)

Comments:

The enzyme, characterized from the bacterium Corynebacterium glutamicum, is a single-component hydroxylase. The enzyme has no activity with NADH. cf. EC 1.14.13.220, resorcinol 4-hydroxylase (NADH), and EC 1.14.14.27, resorcinol 4-hydroxylase (FADH₂).

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Huang, Y., Zhao, K.X., Shen, X.H., Chaudhry, M.T., Jiang, C.Y. and Liu, S.J. Genetic characterization of the resorcinol catabolic pathway in Corynebacterium glutamicum. Appl. Environ. Microbiol. 72 (2006) 7238–7245. [DOI] [PMID: 16963551]

[EC 1.14.13.219 created 2016]