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Your query returned 1 entry. Printable version
EC | 1.14.13.180 | ||||
Accepted name: | aklavinone 12-hydroxylase | ||||
Reaction: | aklavinone + NADPH + H+ + O2 = ε-rhodomycinone + NADP+ + H2O | ||||
For diagram of aflatoxin biosynthesis, click here | |||||
Glossary: | aklavinone = methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate ε-rhodomycinone = methyl (1R,2R,4S)-2-ethyl-2,4,5,7,12-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate |
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Other name(s): | DnrF; RdmE; aklavinone 11-hydroxylase (incorrect) | ||||
Systematic name: | aklavinone,NADPH:oxygen oxidoreductase (12-hydroxylating) | ||||
Comments: | The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. | ||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB | ||||
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