The Enzyme Database

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Accepted name: 2′-deoxymugineic-acid 2′-dioxygenase
Reaction: 2′-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2
For diagram of nicotianamine biosynthesis, click here
Other name(s): IDS3
Systematic name: 2′-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)
Comments: Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2′-deoxymugineic acid to form 3-epihydroxymugineic acid.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 133758-62-0
1.  Nakanishi, H., Yamaguchi, H., Sasakuma, T., Nishizawa, N.K. and Mori, S. Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores. Plant Mol. Biol. 44 (2000) 199–207. [PMID: 11117263]
2.  Kobayashi, T., Nakanishi, H., Takahashi, M., Kawasaki, S., Nishizawa, N.K. and Mori, S. In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2′-deoxymugineic acid to mugineic acid in transgenic rice. Planta 212 (2001) 864–871. [PMID: 11346963]
[EC created 2005]

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