The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: C-glycoside oxidase
Reaction: carminate + O2 = 3′-dehydrocarminate + H2O2
For diagram of carminate catabolism, click here
Glossary: carminate = 7-(β-D-glucopyranosyl)-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-9,10-dihydroanthracene-2-carboxylate
Other name(s): carA (gene name)
Systematic name: carminate:oxygen 3′-oxidoreductase (H2O2-forming)
Comments: A flavoprotein (FAD). This bacterial enzyme participates in degradation of certain C-glucosides by catalysing the oxidation of the hydroxyl group at position 3 of the glycose moiety. The enzyme was found active with assorted C-glycosides, such as carminate, mangiferin, and C6-glycosylated flavonoids, but not with D-glucose or C8-glycosylated flavonoids.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Kumano, T., Hori, S., Watanabe, S., Terashita, Y., Yu, H.Y., Hashimoto, Y., Senda, T., Senda, M. and Kobayashi, M. FAD-dependent C-glycoside-metabolizing enzymes in microorganisms: Screening, characterization, and crystal structure analysis. Proc. Natl. Acad. Sci. USA 118(40) (2021) e2106580118. [DOI] [PMID: 34583991]
[EC created 2022]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald