The Enzyme Database

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Accepted name: alcohol dehydrogenase [NAD(P)+]
Reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+
For diagram of retinal and derivatives biosynthesis, click here
Other name(s): retinal reductase (ambiguous); aldehyde reductase (NADPH/NADH); alcohol dehydrogenase [NAD(P)]
Systematic name: alcohol:NAD(P)+ oxidoreductase
Comments: Reduces aliphatic aldehydes of carbon chain length from 2 to 14, with greatest activity on C4, C6 and C8 aldehydes; also reduces retinal to retinol.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37250-10-5
1.  Fidge, N.H. and Goodman, D.S. The enzymatic reduction of retinal to retinol in rat intestine. J. Biol. Chem. 243 (1968) 4372–4379. [PMID: 4300551]
[EC created 1972]

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