The Enzyme Database

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Accepted name: tetrachlorobenzoquinone reductase
Reaction: 2,3,5,6-tetrachlorohydroquinone + NAD+ = 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH + H+
Other name(s): pcpD (gene name); TCBQ reductase
Systematic name: 2,3,5,6-tetrachlorohydroquinone:NAD+ oxidoreductase
Comments: Contains FMN. The enzyme, characterized from the bacterium Sphingobium chlorophenolicum, participates in the degradation of pentachlorophenol.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Chen, L. and Yang, J. Biochemical characterization of the tetrachlorobenzoquinone reductase involved in the biodegradation of pentachlorophenol. Int. J. Mol. Sci. 9 (2008) 198–212. [PMID: 19325743]
2.  Yadid, I., Rudolph, J., Hlouchova, K. and Copley, S.D. Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol. Proc. Natl. Acad. Sci. USA 110 (2013) E2182–E2190. [DOI] [PMID: 23676275]
[EC created 2017]

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