The Enzyme Database

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Accepted name: farnesol dehydrogenase (NAD+)
Reaction: (2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+
For diagram of juvenile hormone biosynthesis, click here
Other name(s): NAD+-farnesol dehydrogenase
Systematic name: (2E,6E)-farnesol:NAD+ 1-oxidoreductase
Comments: The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. EC, geraniol dehydrogenase (NAD+)]. Unlike EC, farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Noge, K., Kato, M., Mori, N., Kataoka, M., Tanaka, C., Yamasue, Y., Nishida, R. and Kuwahara, Y. Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae). FEBS J. 275 (2008) 2807–2817. [DOI] [PMID: 18422649]
[EC created 2013]

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