ExplorEnz: EC 1.1.1.320

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1.1.1.320

Accepted name:

benzil reductase [(S)-benzoin forming]

Reaction:

(S)-benzoin + NADP⁺ = benzil + NADPH + H⁺

Glossary:

(S)-benzoin = (2S)-2-hydroxy-1,2-diphenylethanone
benzil = 1,2-diphenylethane-1,2-dione

Other name(s):

YueD

Systematic name:

(S)-benzoin:NADP⁺ oxidoreductase

Comments:

The enzyme also reduces 1-phenylpropane-1,2-dione. The enzyme from Bacillus cereus in addition reduces 1,4-naphthoquinone and 1-(4-methylphenyl)-2-phenylethane-1,2-dione with high efficiency [2].

Links to other databases:

BRENDA, EXPASY, Gene, KEGG, MetaCyc

References:

1.	Maruyama, R., Nishizawa, M., Itoi, Y., Ito, S. and Inoue, M. Isolation and expression of a Bacillus cereus gene encoding benzil reductase. Biotechnol. Bioeng. 75 (2001) 630–633. [PMID: 11745140]
2.	Maruyama, R., Nishizawa, M., Itoi, Y., Ito, S. and Inoue, M. The enzymes with benzil reductase activity conserved from bacteria to mammals. J. Biotechnol. 94 (2002) 157–169. [DOI] [PMID: 11796169]

[EC 1.1.1.320 created 2012]