| EC |
1.1.1.277 |
| Accepted name: |
3β-hydroxy-5β-steroid dehydrogenase |
| Reaction: |
3β-hydroxy-5β-pregnane-20-one + NADP+ = 5β-pregnan-3,20-dione + NADPH + H+ |
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For diagram of reaction, click here |
| Other name(s): |
3β-hydroxysteroid 5β-oxidoreductase; 3β-hydroxysteroid 5β-progesterone oxidoreductase |
| Systematic name: |
3β-hydroxy-5β-steroid:NADP+ 3-oxidoreductase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 162731-81-9 |
| References: |
| 1. |
Stuhlemmer, U. and Kreis, W. Cardenolide formation and activity of pregnane-modifying enzymes in cell suspension cultures, shoot cultures and leaves of Digitalis lanata. Plant Physiol. 34 (1996) 85–91. |
| 2. |
Seitz, H.U. and Gaertner, D.E. Enzymes in cardenolide-accumulating shoot cultures of Digitalis purpurea. Plant Cell 38 (1994) 337–344. |
| 3. |
Lindemann, P. and Luckner, M. Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata. Phytochemistry 46 (1997) 507–513. |
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| [EC 1.1.1.277 created 2003] |
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