|Accepted name:||quinate dehydrogenase|
|Reaction:||L-quinate + NAD+ = 3-dehydroquinate + NADH + H+|
|Glossary:||quinate = (1R,3R,4R,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid and is a cyclical carboxylate
The numbering system used for the 3-dehydroquinate is that of the recommendations on cyclitols, sections I-8 and I-9: and is shown in the reaction diagram. The use of the term ’5-dehydroquinate’ for this compound is based on an earlier system of numbering.
|Other name(s):||quinic dehydrogenase; quinate:NAD oxidoreductase; quinate 5-dehydrogenase; quinate:NAD+ 5-oxidoreductase|
|Systematic name:||L-quinate:NAD+ 3-oxidoreductase|
|Comments:||The enzyme is specific for quinate as substrate; phenylpyruvate, phenylalanine, cinnamate and shikimate will not act as substrates. NAD+ cannot be replaced by NADP+.|