Accepted name: gluconate 2-dehydrogenase
Reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+
Other name(s): 2-keto-D-gluconate reductase; 2-ketogluconate reductase
Systematic name: D-gluconate:NADP+ oxidoreductase
Comments: Also acts on L-idonate, D-galactonate and D-xylonate.
1.  Adachi, O., Chiyonobu, T., Shinagawa, E., Matsushita, K. and Ameyama, M. Crystalline 2-ketogluconate reductase from Acetobacter ascendens, the second instance of crystalline enzyme in genus Acetobacter. Agric. Biol. Chem. 42 (1978) 2057.
2.  Chiyonobu, T., Shinagawa, E., Adachi, O. and Ameyama, M. Purification, crystallization and properties of 2-ketogluconate reductase from Acetobacter rancens. Agric. Biol. Chem. 40 (1976) 175–184.
[EC created 1989]

Data © 2001–2020 IUBMB
Web site © 2005–2020 Andrew McDonald