EC |
1.1.1.210 |
Accepted name: |
3β(or 20α)-hydroxysteroid dehydrogenase |
Reaction: |
5α-androstan-3β,17β-diol + NADP+ = 17β-hydroxy-5α-androstan-3-one + NADPH + H+ |
Other name(s): |
progesterone reductase; dehydrogenase, 3β,20α-hydroxy steroid; 3β,20α-hydroxysteroid oxidoreductase |
Systematic name: |
3β(or 20α)-hydroxysteroid:NADP+ oxidoreductase |
Comments: |
Also acts on 20α-hydroxysteroids. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 82869-26-9 |
References: |
1. |
Sharaf, M.A. and Sweet, F. Dual activity at an enzyme active site: 3β,20α-hydroxysteroid oxidoreductase from fetal blood. Biochemistry 21 (1982) 4615–4620. [PMID: 6958329] |
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[EC 1.1.1.210 created 1986] |
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