EC 1.1.1.160     
Accepted name: dihydrobunolol dehydrogenase
Reaction: (±)-5-[(tert-butylamino)-2′-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ = (±)-5-[(tert-butylamino)-2′-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+
Other name(s): bunolol reductase
Systematic name: (±)-5-[(tert-butylamino)-2′-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase
Comments: Also acts, more slowly, with NAD+.
References:
1.  Leinweber, F.-J., Greenough, R.C., Schwender, C.F., Kaplan, H.R. and DiCarlo, F.J. Bunolol metabolism by cell-free preparations of human liver: biosynthesis of dihydrobunolol. Xenobiotica 2 (1972) 191–202. [PMID: 4560367]
[EC 1.1.1.160 created 1976]
 
 


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