The Enzyme Database

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EC 1.1.1.154     
Accepted name: ureidoglycolate dehydrogenase [NAD(P)+]
Reaction: (S)-ureidoglycolate + NAD(P)+ = N-carbamoyl-2-oxoglycine + NAD(P)H + H+
For diagram of AMP catabolism, click here
Other name(s): ureidoglycolate dehydrogenase (ambiguous)
Systematic name: (S)-ureidoglycolate:NAD(P)+ oxidoreductase
Comments: Involved in catabolism of purines. The enzyme from the bacterium Arthrobacter allantoicus can use both NAD+ and NADP+ with similar activity. cf. EC 1.1.1.350, ureidoglycolate dehydrogenase (NAD+).
Links to other databases: BRENDA, EXPASY, GENE, KEGG, MetaCyc, PDB, CAS registry number: 62213-62-1
References:
1.  van der Drift, C., van Helvoort, P.E.M. and Vogels, G.D. S-Ureidoglycolate dehydrogenase: purification and properties. Arch. Biochem. Biophys. 145 (1971) 465–469. [DOI] [PMID: 4399430]
[EC 1.1.1.154 created 1976, modified 2025]
 
 


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