| EC |
1.1.1.154 |
| Accepted name: |
ureidoglycolate dehydrogenase [NAD(P)+] |
| Reaction: |
(S)-ureidoglycolate + NAD(P)+ = N-carbamoyl-2-oxoglycine + NAD(P)H + H+ |
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For diagram of AMP catabolism, click here |
| Other name(s): |
ureidoglycolate dehydrogenase (ambiguous) |
| Systematic name: |
(S)-ureidoglycolate:NAD(P)+ oxidoreductase |
| Comments: |
Involved in catabolism of purines. The enzyme from the bacterium Arthrobacter allantoicus can use both NAD+ and NADP+ with similar activity. cf. EC 1.1.1.350, ureidoglycolate dehydrogenase (NAD+). |
| Links to other databases: |
BRENDA, EXPASY, GENE, KEGG, MetaCyc, PDB, CAS registry number: 62213-62-1 |
| References: |
| 1. |
van der Drift, C., van Helvoort, P.E.M. and Vogels, G.D. S-Ureidoglycolate dehydrogenase: purification and properties. Arch. Biochem. Biophys. 145 (1971) 465–469. [DOI] [PMID: 4399430] |
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| [EC 1.1.1.154 created 1976, modified 2025] |
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