EC |
1.1.1.132 |
Accepted name: |
GDP-mannose 6-dehydrogenase |
Reaction: |
GDP-D-mannose + 2 NAD+ + H2O = GDP-D-mannuronate + 2 NADH + 2 H+ |
Other name(s): |
guanosine diphosphomannose dehydrogenase; GDP-mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase |
Systematic name: |
GDP-D-mannose:NAD+ 6-oxidoreductase |
Comments: |
Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37250-63-8 |
References: |
1. |
Preiss, J. Sugar nucleotide reaction in Arthrobacter. II. Biosynthesis of guanosine diphosphomannuronate. J. Biol. Chem. 239 (1964) 3127–3132. [PMID: 14245351] |
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[EC 1.1.1.132 created 1972] |
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