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© IUBMB 2001
Polysaccharide representation based on Nomenclature of Carbohydrates 2carb-38.5.
For each reaction the new bond between GlcNAC and Man is bold to highlighted its position.
These enzymes probably act in numerical order, except that transferases III and IV probably compete for the same acceptor. The product formed by transferase III is not considered an acceptor for further N-acetylglucosaminyltransferase action. For reviews, see:
1. Palcic, M.M. Glycosyltransferases in glycobiology. Methods Enzymol. 230 (1994) 300-316. [PMID: 8139503]
2. Schachter, H. The joys of HexNAc. The synthesis and function of N- and O-glycan branches. Glycoconj. J. 17 (2000) 465-483. [PMID: 11421343]
EC 188.8.131.52 α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
EC 184.108.40.206 α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
EC 220.127.116.11 β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 18.104.22.168 α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 22.214.171.124 α-1,6-mannosyl-glycoprotein 6-β-N-acetylglucosaminyltransferase
EC 126.96.36.199 α-1,6-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 188.8.131.52 mannosyl-oligosaccharide 1,3-1,6-α-mannosidase