The Enzyme Database

Displaying entries 1-50 of 314.

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EC 1.1.1.70     
Deleted entry:  D-glucuronolactone dehydrogenase. Now included with EC 1.2.1.3 aldehyde dehydrogenase (NAD+)
[EC 1.1.1.70 created 1965, deleted 1978]
 
 
EC 1.1.1.74     
Deleted entry:  D-aminopropanol dehydrogenase (reaction due to EC 1.1.1.4 (R,R)-butanediol dehydrogenase)
[EC 1.1.1.74 created 1972, deleted 1976]
 
 
EC 1.1.1.89     
Deleted entry:  dihydroxyisovalerate dehydrogenase (isomerizing). Now included with EC 1.1.1.86 ketol-acid reductoisomerase
[EC 1.1.1.89 created 1972, deleted 1976]
 
 
EC 1.1.1.128     
Deleted entry: L-idonate 2-dehydrogenase. The reaction described is covered by EC 1.1.1.264.
[EC 1.1.1.128 created 1972, modified 1976, deleted 2012]
 
 
EC 1.1.1.139     
Deleted entry: polyol dehydrogenase (NADP+). Now included with EC 1.1.1.21 aldehyde reductase
[EC 1.1.1.139 created 1972, deleted 1978]
 
 
EC 1.1.1.155     
Deleted entry: homoisocitrate dehydrogenase. The enzyme is identical to EC 1.1.1.87, homoisocitrate dehydrogenase
[EC 1.1.1.155 created 1976, deleted 2004]
 
 
EC 1.1.1.161     
Deleted entry: cholestanetetraol 26-dehydrogenase. The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase
[EC 1.1.1.161 created 1976, deleted 2012]
 
 
EC 1.1.1.180     
Deleted entry:  mannonate dehydrogenase (NAD(P)+). Now included with EC 1.1.1.131 mannuronate reductase
[EC 1.1.1.180 created 1983, deleted 1984]
 
 
EC 1.1.1.182     
Deleted entry:  fenchol dehydrogenase. Now included with EC 1.1.1.198 (+)-borneol dehydrogenase, EC 1.1.1.227 (-)-borneol dehydrogenase and EC 1.1.1.228 (+)-sabinol dehydrogenase
[EC 1.1.1.182 created 1983, deleted 1990]
 
 
EC 1.1.1.249     
Deleted entry: Provisional entry deleted. Revised and reinstated as EC 2.5.1.46 deoxyhypusine synthase
[EC 1.1.1.249 provisional version created 1999, deleted 1999 (reinstated 2001 as EC 2.5.1.46)]
 
 
EC 1.1.1.293     
Deleted entry: tropinone reductase I. This enzyme was already in the Enzyme List as EC 1.1.1.206, tropine dehydrogenase so EC 1.1.1.293 has been withdrawn at the public-review stage
[EC 1.1.1.293 created 2007, withdrawn while undergoing public review]
 
 
EC 1.1.3.1     
Deleted entry:  glycolate oxidase. Now included with EC 1.1.3.15 (S)-2-hydroxy-acid oxidase
[EC 1.1.3.1 created 1961, deleted 1984]
 
 
EC 1.1.3.3     
Deleted entry: malate oxidase. Now classified as EC 1.1.5.4, malate dehydrogenase (quinone).
[EC 1.1.3.3 created 1961, deleted 2014]
 
 
EC 1.1.3.31     
Deleted entry:  methanol oxidase. Cannot be distinguished from EC 1.1.3.13, alcohol oxidase
[EC 1.1.3.31 created 1992, deleted 2003]
 
 
EC 1.1.5.1     
Deleted entry:  cellobiose dehydrogenase (quinone). Now known to be proteolytic product of EC 1.1.99.18, cellobiose dehydrogenase (acceptor)
[EC 1.1.5.1 created 1983, deleted 2002]
 
 
EC 1.2.1.1     
Deleted entry:  glutathione-dependent formaldehyde dehydrogenase. This enzyme was classified on the basis of an incorrect reaction. It has been replaced by two enzymes, EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase
[EC 1.2.1.1 created 1961, modified 1982, modified 2002, deleted 2005]
 
 
EC 1.2.1.6     
Deleted entry:  benzaldehyde dehydrogenase
[EC 1.2.1.6 created 1961, deleted 1965]
 
 
EC 1.2.1.40     
Deleted entry: 3α,7α,12α-trihydroxycholestan-26-al 26-oxidoreductase. The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase
[EC 1.2.1.40 created 1976, deleted 2012]
 
 
EC 1.2.2.2     
Deleted entry: pyruvate dehydrogenase (cytochrome). Now covered by EC 1.2.5.1, pyruvate dehydrogenase (quinone)
[EC 1.2.2.2 created 1961, deleted 2010]
 
 
EC 1.2.3.10     
Deleted entry: carbon-monoxide oxidase. Activity due to EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561)
[EC 1.2.3.10 created 1990, deleted 2003]
 
 
EC 1.2.3.11     
Deleted entry: retinal oxidase. Now included with EC 1.2.3.1, aldehyde oxidase
[EC 1.2.3.11 created 1990, modified 2002, deleted 2011]
 
 
EC 1.2.4.3     
Deleted entry:  2-oxoisocaproate dehydrogenase. Now included with EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
[EC 1.2.4.3 created 1972, deleted 1978]
 
 
EC 1.2.7.2     
Deleted entry: 2-oxobutyrate synthase. Now included with EC 1.2.7.1, pyruvate synthase.
[EC 1.2.7.2 created 1972, deleted 2013]
 
 
EC 1.2.7.9     
Deleted entry: 2-oxoglutarate ferredoxin oxidoreductase. This enzyme is identical to EC 1.2.7.3, 2-oxoglutarate synthase
[EC 1.2.7.9 created 2003, deleted 2005]
 
 
EC 1.3.1.23     
Deleted entry:  cholestenone β-reductase. The enzyme is identical to EC 1.3.1.3, Δ4-3-oxosteroid 5β-reductase
[EC 1.3.1.23 created 1972, deleted 2005]
 
 
EC 1.3.1.50     
Deleted entry:  tetrahydroxynaphthalene reductase. Now EC 1.1.1.252 tetrahydroxynaphthalene reductase
[EC 1.3.1.50 created 1992, deleted 1999]
 
 
EC 1.3.1.55     
Deleted entry:  cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase. Enzyme is identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
[EC 1.3.1.55 created 1999, deleted 2004]
 
 
EC 1.3.1.59     
Deleted entry: 1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase. No evidence in the paper cited that the enzyme exists
[EC 1.3.1.59 created 2000, deleted 2006]
 
 
EC 1.3.1.61     
Deleted entry: terephthalate 1,2-cis-dihydrodiol dehydrogenase. Enzyme is identical to EC 1.3.1.53, (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
[EC 1.3.1.61 created 2000, deleted 2007]
 
 
EC 1.3.99.1     
Deleted entry: succinate dehydrogenase. The activity is included in EC 1.3.5.1, succinate dehydrogenase (quinone).
[EC 1.3.99.1 created 1961, deleted 2014]
 
 
EC 1.4.1.6     
Deleted entry: D-proline reductase. Now included with EC 1.21.4.1, D-proline reductase (dithiol)
[EC 1.4.1.6 created 1961, deleted 1982]
 
 
EC 1.4.1.22     
Deleted entry: ornithine cyclodeaminase. It was pointed out during the public-review process that there is no overall consumption of NAD+ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official
[EC 1.4.1.22 created 2006, deleted 2006]
 
 
EC 1.4.3.6     
Deleted entry: amine oxidase (copper-containing). This was classified on the basis of cofactor content rather than reaction catalysed and is now known to contain two distinct enzyme activities. It has been replaced by two enzymes, EC 1.4.3.21 (primary-amine oxidase) and EC 1.4.3.22 (diamine oxidase)
[EC 1.4.3.6 created 1961, modified 1983, modified 1989, deleted 2008]
 
 
EC 1.4.3.9     
Deleted entry:  tyramine oxidase. Now included with EC 1.4.3.4 amine oxidase (flavin-containing)
[EC 1.4.3.9 created 1972, deleted 1984]
 
 
EC 1.4.3.18     
Deleted entry: cytokinin oxidase. Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12, cytokinin dehydrogenase)
[EC 1.4.3.18 proposed 2000]
 
 
EC 1.5.1.4     
Deleted entry:  dihydrofolate dehydrogenase. Now included with EC 1.5.1.3 dihydrofolate reductase
[EC 1.5.1.4 created 1961, deleted 1976]
 
 
EC 1.5.1.14     
Deleted entry:  1,2-didehydropipecolate reductase. Now included with EC 1.5.1.21 Δ1-piperideine-2-carboxylate reductase
[EC 1.5.1.14 created 1976, deleted 1989]
 
 
EC 1.5.1.29     
Deleted entry: FMN reductase [NAD(P)H]. Now covered by EC 1.5.1.38 [FMN reductase (NADPH)], EC 1.5.1.39 [FMN reductase [NAD(P)H])] and EC 1.5.1.41 (riboflavin reductase [NAD(P)H])
[EC 1.5.1.29 created 1981 as EC 1.6.8.1, transferred 2002 to EC 1.5.1.29, modified 2002, deleted 2011]
 
 
EC 1.5.1.35     
Deleted entry: 1-pyrroline dehydrogenase. The enzyme is identical to EC 1.2.1.19, aminobutyraldehyde dehydrogenase, as the substrates 1-pyrroline and 4-aminobutanal are interconvertible
[EC 1.5.1.35 created 2006, deleted 2007]
 
 
EC 1.5.3.3     
Deleted entry:  spermine oxidase
[EC 1.5.3.3 created 1961, deleted 1972]
 
 
EC 1.5.3.8     
Deleted entry: (S)-tetrahydroprotoberberine oxidase. Now included with EC 1.3.3.8, tetrahydroberberine oxidase
[EC 1.5.3.8 created 1989, deleted 1992]
 
 
EC 1.5.3.11     
Deleted entry: polyamine oxidase. Now included with EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (N8-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase)
[EC 1.5.3.11 created 1992, deleted 2009]
 
 
EC 1.6.2.3     
Deleted entry:  cytochrome reductase (NADPH)
[EC 1.6.2.3 created 1972, deleted 1965]
 
 
EC 1.6.5.1     
Deleted entry:  quinone reductase
[EC 1.6.5.1 created 1961, deleted 1965]
 
 
EC 1.6.99.10     
Deleted entry: dihydropteridine reductase (NADH). Now included with EC 1.5.1.34, 6,7-dihydropteridine reductase
[EC 1.6.99.10 created 1978, deleted 1981]
 
 
EC 1.7.1.8     
Deleted entry:  withdrawn in the light of further information on the acceptor
[EC 1.7.1.8 created 2002, deleted 2002]
 
 
EC 1.7.99.2     
Deleted entry:  nitric-oxide reductase. Reaction may have been due to the combined action of EC 1.7.99.6 nitrous-oxide reductase and EC 1.7.99.7 nitric-oxide reductase
[EC 1.7.99.2 created 1961, modified 1976, deleted 1992]
 
 
EC 1.7.99.5     
Deleted entry:  5,10-methylenetetrahydrofolate reductase (FADH2). Now included with EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]. Based on the reference, it had been thought that this was a separate enzyme from EC 1.5.1.20 but the reference upon which the entry was based has since been disproved
[EC 1.7.99.5 created 1965 as EC 1.1.1.68, transferred 1978 to EC 1.1.99.15, transferred 1980 to EC 1.7.99.5, deleted 2005]
 
 
EC 1.8.1.1     
Deleted entry:  cysteamine dehydrogenase
[EC 1.8.1.1 created 1961, deleted 1972]
 
 
EC 1.8.6.1     
Deleted entry:  Nitrate-ester reductase. Now included with EC 2.5.1.18 glutathione transferase
[EC 1.8.6.1 created 1961, deleted 1976]
 
 


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