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Your query returned 3 entries. Printable version
EC | 2.1.1.338 | ||||
Accepted name: | desmethylxanthohumol 6′-O-methyltransferase | ||||
Reaction: | S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol | ||||
For diagram of xanthohumol biosynthesis, click here | |||||
Glossary: | desmethylxanthohumol = 2′,4,4′,6′-tetrahydroxy-3-prenylchalcone = (2E)-3-(4-hydroxyphenyl)-1-[2,4,6-trihydroxy-3-(3-methylbut-2-en-1-yl)phenyl]prop-2-en-1-one xanthohumol = 2′,4,4′-trihydroxy-6′-methoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
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Other name(s): | OMT1 (ambiguous) | ||||
Systematic name: | S-adenosyl-L-methionine:desmethylxanthohumol 6′-O-methyltransferase | ||||
Comments: | Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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EC | 2.1.1.339 | ||||
Accepted name: | xanthohumol 4-O-methyltransferase | ||||
Reaction: | S-adenosyl-L-methionine + xanthohumol = S-adenosyl-L-homocysteine + 4-O-methylxanthohumol | ||||
For diagram of xanthohumol biosynthesis, click here | |||||
Glossary: | xanthohumol = 2′,4,4′-trihydroxy-6′-methoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one 4-O-methylxanthohumol =2′,4′-dihydroxy-4,6′-dimethoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one |
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Other name(s): | OMT2 (ambiguous); S-adenosyl-L-methionine:xanthohumol 4′-O-methyltransferase (incorrect); xanthohumol 4′-O-methyltransferase (incorrect) | ||||
Systematic name: | S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase | ||||
Comments: | The enzyme from hops (Humulus lupulus) has a broad substrate specificity. The best substrates in vitro are resveratrol, desmethylxanthohumol, naringenin chalcone and isoliquiritigenin. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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EC | 2.5.1.136 | ||||
Accepted name: | 2-acylphloroglucinol 4-prenyltransferase | ||||
Reaction: | prenyl diphosphate + a 2-acylphloroglucinol = diphosphate + a 2-acyl-4-prenylphloroglucinol | ||||
Glossary: | naringenin chalcone = 2′,4,4′,6′-tetrahydroxychalcone = 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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Other name(s): | PT-1 (gene name); PT1L (gene name); aromatic prenyltransferase (ambiguous); dimethylallyl-diphosphate:2-acylphloroglucinol 4-dimethylallyltransferase | ||||
Systematic name: | prenyl-diphosphate:2-acylphloroglucinol 4-prenyltransferase | ||||
Comments: | The enzyme, characterized from hop (Humulus lupulus), acts on phlorisovalerophenone, phlormethylbutanophenone, and phlorisobutanophenone during the synthesis of bitter acids. It also acts with much lower activity on naringenin chalcone. Forms a complex with EC 2.5.1.137, 2-acyl-4-prenylphloroglucinol 6-prenyltransferase, which catalyses additional prenylation reactions. Requires Mg2+. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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