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Your query returned 1 entry. Printable version
EC | 2.3.1.158 | ||
Accepted name: | phospholipid:diacylglycerol acyltransferase | ||
Reaction: | phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol | ||
Glossary: | ricinoleic acid = (9Z,12R)-12-hydroxyoctadec-9-enoic acid vernolic acid = (9Z,12S,13R)-12,13-epoxyoctadec-9-enoic acid |
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Other name(s): | PDAT | ||
Systematic name: | phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase | ||
Comments: | This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk’s beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 288587-47-3 | ||
References: |
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