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Your query returned 4 entries. Printable version
EC | 1.14.13.175 | ||||||||
Transferred entry: | aflatoxin B synthase. Now EC 1.14.14.117, aflatoxin B synthase | ||||||||
EC | 1.14.14.117 | ||||||||
Accepted name: | aflatoxin B synthase | ||||||||
Reaction: | (1) 8-O-methylsterigmatocystin + 2 [reduced NADPH—hemoprotein reductase] + 2 O2 = aflatoxin B1 + 2 [oxidized NADPH—hemoprotein reductase] + H2O + methanol + CO2 (2) 8-O-methyldihydrosterigmatocystin + 2 [reduced NADPH—hemoprotein reductase] + 2 O2 = aflatoxin B2 + 2 [oxidized NADPH—hemoprotein reductase] + H2O + methanol + CO2 |
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For diagram of aflatoxin biosynthesis (part 4), click here | |||||||||
Glossary: | aflatoxin B1 = (6aR,9aS)-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione aflatoxin B2 = (6aR,9aS)-4-methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione 8-O-methylsterigmatocystin = 6,8-dimethoxy-3a,12c-dihydrofuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one 8-O-methyldihydrosterigmatocystin = 6,8-dimethoxy-1,2,3a,12c-tetrahydrofuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one |
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Other name(s): | ordA (gene name) | ||||||||
Systematic name: | 8-O-methylsterigmatocystin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B-forming) | ||||||||
Comments: | A cytochrome P-450 (heme-thiolate) protein. Isolated from the mold Aspergillus parasiticus. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 2.1.1.109 | ||||||||
Accepted name: | demethylsterigmatocystin 6-O-methyltransferase | ||||||||
Reaction: | S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-homocysteine + sterigmatocystin | ||||||||
For diagram of sterigmatocystin biosynthesis, click here | |||||||||
Other name(s): | demethylsterigmatocystin methyltransferase; O-methyltransferase I | ||||||||
Systematic name: | S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase | ||||||||
Comments: | Dihydrodemethylsterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 123516-47-2 | ||||||||
References: |
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EC | 2.1.1.110 | ||||||||
Accepted name: | sterigmatocystin 8-O-methyltransferase | ||||||||
Reaction: | (1) S-adenosyl-L-methionine + sterigmatocystin = S-adenosyl-L-homocysteine + 8-O-methylsterigmatocystin (2) S-adenosyl-L-methionine + dihydrosterigmatocystin = S-adenosyl-L-homocysteine + 8-O-methyldihydrosterigmatocystin |
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For diagram of sterigmatocystin biosynthesis, click here | |||||||||
Glossary: | sterigmatocystin = 3a,12c-dihydro-8-hydroxy-6-methoxyfuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one dihydrosterigmatocystin = 1,2,3a,12c-tetrahydro-8-hydroxy-6-methoxyfuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one 8-O-methylsterigmatocystin = 6,8-dimethoxy-3a,12c-dihydrofuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one 8-O-methyldihydrosterigmatocystin = 6,8-dimethoxy-1,2,3a,12c-tetrahydrofuro[3′,2′:4,5]furo[2,3-c]xanthen-7-one |
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Other name(s): | sterigmatocystin methyltransferase; O-methyltransferase II; sterigmatocystin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase (incorrect); OmtA | ||||||||
Systematic name: | S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase | ||||||||
Comments: | Dihydrosterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 116958-29-3 | ||||||||
References: |
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