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Your query returned 4 entries. Printable version
EC | 1.8.1.3 | ||||||||||
Deleted entry: | hypotaurine dehydrogenase. The reaction is now known to be catalyzed by EC 1.14.13.8, flavin-containing monooxygenase. | ||||||||||
EC | 1.13.11.19 | ||||||||||
Accepted name: | cysteamine dioxygenase | ||||||||||
Reaction: | cysteamine + O2 = hypotaurine | ||||||||||
For diagram of taurine biosynthesis, click here | |||||||||||
Glossary: | cysteamine = 2-aminoethanethiol | ||||||||||
Other name(s): | ADO (gene name); persulfurase; cysteamine oxygenase; cysteamine:oxygen oxidoreductase | ||||||||||
Systematic name: | 2-aminoethanethiol:oxygen oxidoreductase | ||||||||||
Comments: | A non-heme iron protein that is involved in the biosynthesis of taurine. 3-Aminopropanethiol (homocysteamine) and 2-sulfanylethan-1-ol (2-mercaptoethanol) can also act as substrates, but glutathione, cysteine, and cysteine ethyl- and methyl esters are not good substrates [1,3]. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9033-41-4 | ||||||||||
References: |
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EC | 2.6.1.77 | ||||||||||
Accepted name: | taurine—pyruvate aminotransferase | ||||||||||
Reaction: | taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde | ||||||||||
For diagram of reaction, click here | |||||||||||
Glossary: | taurine = 2-aminoethanesulfonate hypotaurine = 2-aminoethanesulfinate 2-sulfoacetaldehyde = 2-oxoethanesulfonate 2-sulfinoacetaldehyde = 2-oxoethanesulfinate |
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Other name(s): | Tpa | ||||||||||
Systematic name: | taurine:pyruvate aminotransferase | ||||||||||
Comments: | The enzyme from the bacterium Bilophila wadsworthia requires pyridoxal 5′-phosphate as a cofactor, and catalyses a reversible reaction that starts an anaerobic taurine degradation pathway. β-Alanine is also a significant amino group donor. The enzyme from the bacterium Pseudomonas denitrificans PD1222 can also use hypotaurine, producing 2-sulfinoacetaldehyde, which spontaneously hydrolyses to sulfite and acetaldehyde. Unlike, EC 2.6.1.55, taurine—2-oxoglutarate transaminase, 2-oxoglutarate cannot serve as an acceptor for the amino group. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 51901-18-9 | ||||||||||
References: |
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EC | 4.1.1.29 | ||||||||||
Accepted name: | sulfinoalanine decarboxylase | ||||||||||
Reaction: | 3-sulfino-L-alanine = hypotaurine + CO2 | ||||||||||
For diagram of taurine biosynthesis, click here | |||||||||||
Other name(s): | cysteine-sulfinate decarboxylase; L-cysteinesulfinic acid decarboxylase; cysteine-sulfinate decarboxylase; CADCase/CSADCase; CSAD; cysteic decarboxylase; cysteinesulfinic acid decarboxylase; cysteinesulfinate decarboxylase; sulfoalanine decarboxylase; 3-sulfino-L-alanine carboxy-lyase | ||||||||||
Systematic name: | 3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming) | ||||||||||
Comments: | A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992 edition of the Enzyme List erroneously gave the name sulfoalanine decarboxylase to this enzyme. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 62213-10-9 | ||||||||||
References: |
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