EC |
1.13.11.68 |
Accepted name: |
9-cis-β-carotene 9′,10′-cleaving dioxygenase |
Reaction: |
9-cis-β-carotene + O2 = 9-cis-10′-apo-β-carotenal + β-ionone |
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For diagram of strigol biosynthesis, click here |
Glossary: |
β-ionone = (3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one |
Other name(s): |
CCD7 (gene name); MAX3 (gene name); NCED7 (gene name) |
Systematic name: |
9-cis-β-carotene:oxygen oxidoreductase (9′,10′-cleaving) |
Comments: |
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Booker, J., Auldridge, M., Wills, S., McCarty, D., Klee, H. and Leyser, O. MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Curr. Biol. 14 (2004) 1232–1238. [DOI] [PMID: 15268852] |
2. |
Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H., Beyer, P. and Al-Babili, S. The path from β-carotene to carlactone, a strigolactone-like plant hormone. Science 335 (2012) 1348–1351. [DOI] [PMID: 22422982] |
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[EC 1.13.11.68 created 2012] |
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EC |
1.13.11.69 |
Accepted name: |
carlactone synthase |
Reaction: |
9-cis-10′-apo-β-carotenal + 2 O2 = carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal |
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For diagram of strigol biosynthesis, click here |
Glossary: |
carlactone = 3-methyl-5-{[(1Z,3E)-2-methyl-4-(2,6,6-trimethylcyclohex-1-en-1-yl)buta-1,3-dien-1-yl]oxy}-5H-furan-2-one |
Other name(s): |
CCD8 (gene name); MAX4 (gene name); NCED8 (gene name) |
Systematic name: |
9-cis-10′-apo-β-carotenal:oxygen oxidoreductase (14,15-cleaving, carlactone-forming) |
Comments: |
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza. Also catalyses EC 1.13.11.70, all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase, but 10-fold slower. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Sorefan, K., Booker, J., Haurogne, K., Goussot, M., Bainbridge, K., Foo, E., Chatfield, S., Ward, S., Beveridge, C., Rameau, C. and Leyser, O. MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea. Genes Dev. 17 (2003) 1469–1474. [DOI] [PMID: 12815068] |
2. |
Schwartz, S.H., Qin, X. and Loewen, M.C. The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching. J. Biol. Chem. 279 (2004) 46940–46945. [DOI] [PMID: 15342640] |
3. |
Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H., Beyer, P. and Al-Babili, S. The path from β-carotene to carlactone, a strigolactone-like plant hormone. Science 335 (2012) 1348–1351. [DOI] [PMID: 22422982] |
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[EC 1.13.11.69 created 2012] |
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EC |
1.13.11.70 |
Accepted name: |
all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase |
Reaction: |
all-trans-10′-apo-β-carotenal + O2 = 13-apo-β-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial |
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For diagram of 10′-apo-β-carotenal biosynthesis, click here |
Other name(s): |
CCD8 (gene name); MAX4 (gene name); NCED8 (gene name); all-trans-10′-apo-β-carotenal:O2 oxidoreductase (13,14-cleaving) |
Systematic name: |
all-trans-10′-apo-β-carotenal:oxygen oxidoreductase (13,14-cleaving) |
Comments: |
Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Schwartz, S.H., Qin, X. and Loewen, M.C. The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching. J. Biol. Chem. 279 (2004) 46940–46945. [DOI] [PMID: 15342640] |
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[EC 1.13.11.70 created 2012] |
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EC |
5.2.1.14 |
Accepted name: |
β-carotene isomerase |
Reaction: |
all-trans-β-carotene = 9-cis-β-carotene |
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For diagram of strigol biosynthesis, click here |
Other name(s): |
DWARF27 (gene name) |
Systematic name: |
β-carotene 9-cis-all-trans isomerase |
Comments: |
The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Lin, H., Wang, R., Qian, Q., Yan, M., Meng, X., Fu, Z., Yan, C., Jiang, B., Su, Z., Li, J. and Wang, Y. DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth. Plant Cell 21 (2009) 1512–1525. [DOI] [PMID: 19470589] |
2. |
Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H., Beyer, P. and Al-Babili, S. The path from β-carotene to carlactone, a strigolactone-like plant hormone. Science 335 (2012) 1348–1351. [DOI] [PMID: 22422982] |
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[EC 5.2.1.14 created 2012] |
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