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Your query returned 9 entries. 
Printable version
| EC | 1.1.1.313 | ||||||||
| Accepted name: | sulfoacetaldehyde reductase (NADPH) | ||||||||
| Reaction: | isethionate + NADP+ = 2-sulfoacetaldehyde + NADPH + H+ | ||||||||
| Glossary: | isethionate = 2-hydroxyethanesulfonate 2-sulfoacetaldehyde = 2-oxoethanesulfonate |
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| Other name(s): | isfD (gene name) | ||||||||
| Systematic name: | isethionate:NADP+ oxidoreductase | ||||||||
| Comments: | Catalyses the reaction only in the opposite direction. Involved in taurine degradation. The bacterium Chromohalobacter salexigens strain DSM 3043 possesses two enzymes that catalyse this reaction, a constitutive enzyme (encoded by isfD2) and an inducible enzyme (encoded by isfD). The latter is induced by taurine, and is responsible for most of the activity observed in taurine-grown cells. cf. EC 1.1.1.433, sulfoacetaldehyde reductase (NADH). | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
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| EC | 1.1.1.433 | ||||||||
| Accepted name: | sulfoacetaldehyde reductase (NADH) | ||||||||
| Reaction: | isethionate + NAD+ = 2-sulfoacetaldehyde + NADH + H+ | ||||||||
| Glossary: | isethionate = 2-hydroxyethanesulfonate 2-sulfoacetaldehyde = 2-oxoethanesulfonate |
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| Other name(s): | sarD (gene name); tauF (gene name); sqwF (gene name); BkTauF | ||||||||
| Systematic name: | isethionate:NAD+ oxidoreductase | ||||||||
| Comments: | The enzymes from the bacteria Bilophila wadsworthia and Clostridium sp. MSTE9 catalyse the reaction only in the reduction direction. In the bacterium Bifidobacterium kashiwanohense the optimal reaction pH for sulfoacetaldehyde reduction is 7.5, while that for isethionate oxidation is 10.0. cf. EC 1.1.1.313, sulfoacetaldehyde reductase (NADPH). | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
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| EC | 1.2.1.73 | ||||||||
| Accepted name: | sulfoacetaldehyde dehydrogenase | ||||||||
| Reaction: | 2-sulfoacetaldehyde + H2O + NAD+ = sulfoacetate + NADH + 2 H+ | ||||||||
| Glossary: | 2-sulfoacetaldehyde = 2-oxoethanesulfonate taurine = 2-aminoethanesulfonate |
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| Other name(s): | SafD | ||||||||
| Systematic name: | 2-sulfoacetaldehyde:NAD+ oxidoreductase | ||||||||
| Comments: | This reaction is part of a bacterial pathway that can utilize the amino group of taurine as a sole source of nitrogen for growth. At physiological concentrations, NAD+ cannot be replaced by NADP+. The enzyme is specific for sulfoacetaldehyde, as formaldehyde, acetaldehyde, betaine aldehyde, propanal, glyceraldehyde, phosphonoacetaldehyde, glyoxylate, glycolaldehyde and 2-oxobutyrate are not substrates. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
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| EC | 1.2.1.81 | ||||||||
| Accepted name: | sulfoacetaldehyde dehydrogenase (acylating) | ||||||||
| Reaction: | 2-sulfoacetaldehyde + CoA + NADP+ = sulfoacetyl-CoA + NADPH + H+ | ||||||||
| Glossary: | 2-sulfoacetaldehyde = 2-oxoethanesulfonate | ||||||||
| Other name(s): | SauS | ||||||||
| Systematic name: | 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating) | ||||||||
| Comments: | The enzyme is involved in degradation of sulfoacetate. In this pathway the reaction is catalysed in the reverse direction. The enzyme is specific for sulfoacetaldehyde and NADP+. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
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| EC | 1.4.99.2 | ||||||||
| Accepted name: | taurine dehydrogenase | ||||||||
| Reaction: | taurine + H2O + acceptor = 2-sulfoacetaldehyde + NH3 + reduced acceptor | ||||||||
| Glossary: | 2-sulfoacetaldehyde = 2-oxoethanesulfonate taurine = 2-aminoethanesulfonate |
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| Other name(s): | taurine:(acceptor) oxidoreductase (deaminating) | ||||||||
| Systematic name: | taurine:acceptor oxidoreductase (deaminating) | ||||||||
| Links to other databases: | BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, CAS registry number: 50812-14-1 | ||||||||
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| EC | 2.3.3.15 | ||||||||
| Accepted name: | sulfoacetaldehyde acetyltransferase | ||||||||
| Reaction: | acetyl phosphate + sulfite = 2-sulfoacetaldehyde + phosphate | ||||||||
| Glossary: | 2-sulfoacetaldehyde = 2-oxoethanesulfonate | ||||||||
| Other name(s): | Xsc | ||||||||
| Systematic name: | acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming) | ||||||||
| Comments: | The reaction occurs in the reverse direction to that shown above. Requires Mg2+. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 56941-15-2 | ||||||||
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| EC | 2.6.1.55 | ||||||||
| Accepted name: | taurine—2-oxoglutarate transaminase | ||||||||
| Reaction: | taurine + 2-oxoglutarate = 2-sulfoacetaldehyde + L-glutamate | ||||||||
| Glossary: | 2-sulfoacetaldehyde = 2-oxoethanesulfonate taurine = 2-aminoethanesulfonate |
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| Other name(s): | taurine aminotransferase; taurine transaminase; taurine—α-ketoglutarate aminotransferase; taurine—glutamate transaminase | ||||||||
| Systematic name: | taurine:2-oxoglutarate aminotransferase | ||||||||
| Comments: | A pyridoxal-phosphate protein. Also acts on D,L-3-amino-isobutanoate, β-alanine and 3-aminopropanesulfonate. Involved in the microbial utilization of β-alanine. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9076-52-2 | ||||||||
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| EC | 2.6.1.77 | ||||||||
| Accepted name: | taurine—pyruvate aminotransferase | ||||||||
| Reaction: | taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde | ||||||||
| For diagram of reaction, click here | |||||||||
| Glossary: | taurine = 2-aminoethanesulfonate hypotaurine = 2-aminoethanesulfinate 2-sulfoacetaldehyde = 2-oxoethanesulfonate 2-sulfinoacetaldehyde = 2-oxoethanesulfinate |
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| Other name(s): | Tpa | ||||||||
| Systematic name: | taurine:pyruvate aminotransferase | ||||||||
| Comments: | The enzyme from the bacterium Bilophila wadsworthia requires pyridoxal 5′-phosphate as a cofactor, and catalyses a reversible reaction that starts an anaerobic taurine degradation pathway. β-Alanine is also a significant amino group donor. The enzyme from the bacterium Pseudomonas denitrificans PD1222 can also use hypotaurine, producing 2-sulfinoacetaldehyde, which spontaneously hydrolyses to sulfite and acetaldehyde. Unlike, EC 2.6.1.55, taurine—2-oxoglutarate transaminase, 2-oxoglutarate cannot serve as an acceptor for the amino group. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 51901-18-9 | ||||||||
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| EC | 4.1.1.79 | ||||||||
| Accepted name: | sulfopyruvate decarboxylase | ||||||||
| Reaction: | 3-sulfopyruvate = 2-sulfoacetaldehyde + CO2 | ||||||||
| For diagram of coenzyme-M biosynthesis, click here | |||||||||
| Glossary: | thiamine diphosphate = 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-diphosphoethyl)-4-methyl-1,3-thiazolium 2-sulfoacetaldehyde = 2-oxoethanesulfonate |
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| Other name(s): | sulfopyruvate carboxy-lyase | ||||||||
| Systematic name: | 3-sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming) | ||||||||
| Comments: | Requires thiamine diphosphate. Does not decarboxylate pyruvate or phosphonopyruvate. The enzyme appears to be oxygen-sensitive. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 303155-97-7 | ||||||||
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