EC |
7.2.2.4 |
Accepted name: |
ABC-type Na+ transporter |
Reaction: |
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2] |
Other name(s): |
natAB (gene names) |
Systematic name: |
ATP phosphohydrolase (ABC-type, Na+-exporting) |
Comments: |
ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. This bacterial enzyme, characterized from Bacillus subtilis, exports Na+ ions out of the cell. cf. EC 7.2.2.1, Na+-transporting two-sector ATPase and EC 7.2.2.3, P-type Na+ transporter. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Cheng, J., Guffanti, A.A. and Krulwich, T.A. A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore. Mol. Microbiol. 23 (1997) 1107–1120. [DOI] [PMID: 9106203] |
2. |
Ogura, M., Tsukahara, K., Hayashi, K. and Tanaka, T. The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion. Microbiology 153 (2007) 667–675. [PMID: 17322186] |
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[EC 7.2.2.4 created 2018] |
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